ORIGINAL ARTICLE: Effect of Cyclosporine on Reperfusion Injury in Acute Myocardial Infarction
Mercredi 30 Juillet 2008 - 06:55 - 5 mois, 1 semaine depuis
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Santé
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New England Journal of Medicin
Experimental evidence suggests that cyclosporine may attenuate myocardial reperfusion injury. In a pilot trial, 58 patients with acute ST-elevation myocardial infarction were randomly assigned to receive an intravenous bolus of either cyclosporine or saline immediately before undergoing percutaneous coronary intervention. Creatine kinase release was significantly reduced in the patients who received cyclosporine. These results require confirmation in a larger trial.