Dernières entêtes d'Actus
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A Double-Blind, Delayed-Start Trial of Rasagiline in Parkinson's Disease
Mercredi 23 Septembre 2009 - 08:56 - 5 mois, 3 semaines depuis - Santé - New England Journal of Medicin This double-blind trial was designed to determine whether rasagiline slows the progression of Parkinson's disease. As compared with delayed treatment, early treatment with rasagiline at a dose of 1 mg per day achieved benefits consistent with a disease-modifying effect, but 2 mg per day did not result in similar benefits. |
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Medical Progress: Renal Failure in Cirrhosis
Mercredi 23 Septembre 2009 - 08:56 - 5 mois, 3 semaines depuis - Santé - New England Journal of Medicin Renal failure, a challenging complication of cirrhosis, is one of the most important risk factors for liver transplantation. In recent years, substantial progress has been made toward understanding the pathogenesis and natural history of renal failure in cirrhosis. This review discusses recently identified information about renal failure in cirrhosis and clinical interventions that may assist in the prevention and management of this complication. |
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Pelvic Spleen
Mercredi 23 Septembre 2009 - 08:56 - 5 mois, 3 semaines depuis - Santé - New England Journal of Medicin A healthy, 23-year-old, nulliparous woman presented with lower abdominal pain, which she reported having had intermittently for the previous year. She had no other symptoms of gastrointestinal distress. A peripheral-blood ... |
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Diagnostic Finding in the Iris
Mercredi 23 Septembre 2009 - 08:56 - 5 mois, 3 semaines depuis - Santé - New England Journal of Medicin A 51-year-old woman was found to have a small, pinkish tumor of the left iris (Panels A and B, arrows). The visual acuity was not affected, and the intraocular pressure ... |
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Case 30-2009 -- A 77-Year-Old Man with Recurrent Transitional-Cell Carcinoma of the Ureter
Mercredi 23 Septembre 2009 - 08:56 - 5 mois, 3 semaines depuis - Santé - New England Journal of Medicin A 77-year-old man was seen at this hospital because of a mass in the left ureter and cytologic examination of a urine specimen that was positive for transitional-cell carcinoma. Eight years earlier, right nephroureterectomy was performed because of transitional-cell carcinoma of the right renal pelvis. Several years later, cytologic examination of urine specimens was positive for transitional-cell carcinoma, but no tumor was evident on examination until 10 months before evaluation, when circumferential thickening of the left ureter was seen on imaging studies. A management decision was made. |
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An Old AML Drug Revisited
Mercredi 23 Septembre 2009 - 08:56 - 5 mois, 3 semaines depuis - Santé - New England Journal of Medicin Acute myeloid leukemia (AML) is a heterogeneous hematologic cancer whose wide range of outcomes probably reflects the accumulation of various acquired mutations that block the differentiation of blood-cell progenitors or ... |
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Rendering the Leukemia Cell Susceptible to Attack
Mercredi 23 Septembre 2009 - 08:56 - 5 mois, 3 semaines depuis - Santé - New England Journal of Medicin In mice, short-term treatment with interferon-{alpha} pushes dormant hematopoietic stem cells into a state of proliferation. This finding may be relevant to the treatment of patients with chronic myelogenous leukemia, and treatment may be more effective if patients are first "primed" with interferon-{alpha}. |
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The Delayed-Start Study Design
Mercredi 23 Septembre 2009 - 08:56 - 5 mois, 3 semaines depuis - Santé - New England Journal of Medicin Delayed-start study designs are a new way to distinguish a treatment's effects on long-term disease progression from its potential short-term effects on disease symptoms. In this article, the strengths, weaknesses, and key design assumptions of this type of trial are examined. |
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Treating Childhood Leukemia without Cranial Irradiation
Mercredi 23 Septembre 2009 - 08:56 - 5 mois, 3 semaines depuis - Santé - New England Journal of Medicin To the Editor: Pui and colleagues (June 25 issue)1 report a high likelihood of event-free and overall survival among children ... |
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Clopidogrel plus Aspirin in Atrial Fibrillation
Mercredi 23 Septembre 2009 - 08:56 - 5 mois, 3 semaines depuis - Santé - New England Journal of Medicin To the Editor: The investigators of ACTIVE (Atrial Fibrillation Clopidogrel Trial with Irbesartan for Prevention of Vascular Events) (May 14 ... |
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