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Hormonal Therapies for Prostate Cancer Increase Risk for Heart Disease
Jeudi 24 Septembre 2009 - 10:54 - 5 mois, 3 semaines depuis   -  Cancérologie  -  Medscape cancérologie
A huge Swedish study shows an increased risk for all types of cardiovascular disease in men taking hormonal therapies for prostate cancer. Medscape Medical News
High-Dose Daunorubicin is a New Standard in AML
Jeudi 24 Septembre 2009 - 08:28 - 5 mois, 3 semaines depuis   -  Cancérologie  -  Medscape cancérologie
A long-time treatment for acute myeloid leukemia, daunorubicin, is more effective at a higher dose in some patients. Medscape Medical News
Sorafenib Shows Promise in Breast Cancer in Phase 2 Study
Mercredi 23 Septembre 2009 - 12:15 - 5 mois, 3 semaines depuis   -  Cancérologie  -  Medscape cancérologie
When added to capecitabine, sorafenib improved the progression-free survival of patients with locally advanced or metastatic breast cancer. Medscape Medical News
FDA Safety Changes: Metronidazole Injection, DexFerrum, INFeD, Tasigna
Mercredi 23 Septembre 2009 - 11:28 - 5 mois, 3 semaines depuis   -  Cancérologie  -  Medscape cancérologie
The FDA has approved safety labeling revisions for metronidazole injection, iron dextran injection (DexFerrum and INFeD), and nilotinib HCl monohydrate capsules (Tasigna). Medscape Medical News
"Dose-Dense" Chemotherapy Regimen May Improve Outcomes in Advanced Ovarian Cancer
Mercredi 23 Septembre 2009 - 11:09 - 5 mois, 3 semaines depuis   -  Cancérologie  -  Medscape cancérologie
In a randomized controlled trial, women with advanced ovarian cancer who received a more intensive "dose-dense" chemotherapy regimen had better overall and progression-free survival. Medscape Medical News
Risk of Confusion in Dosing Tamiflu Oral Suspension in Children
Mercredi 23 Septembre 2009 - 10:19 - 5 mois, 3 semaines depuis   -  Santé  -  New England Journal of Medicin
(No abstract is available for this citation)
Doctors as the Key to Health Care Reform
Mercredi 23 Septembre 2009 - 08:56 - 5 mois, 3 semaines depuis   -  Santé  -  New England Journal of Medicin
Experts agree that sustainable health care reform requires reining in rising costs, but few people understand that the control of medical expenditures is largely in the hands of the medical ...
High-Dose Daunorubicin in Older Patients with Acute Myeloid Leukemia
Mercredi 23 Septembre 2009 - 08:56 - 5 mois, 3 semaines depuis   -  Santé  -  New England Journal of Medicin
Patients with acute myeloid leukemia (AML) who were more than 60 years of age received treatment to induce a complete remission that consisted of cytarabine and daunorubicin; the latter was given at a dose of either 45 mg per square meter of body-surface area (the conventional dose of the drug) or 90 mg per square meter. As compared with patients who received the conventional dose of daunorubicin, those who received the high dose had a significantly higher rate of complete remission without an increase in toxic effects.
Anthracycline Dose Intensification in Acute Myeloid Leukemia
Mercredi 23 Septembre 2009 - 08:56 - 5 mois, 3 semaines depuis   -  Santé  -  New England Journal of Medicin
Patients with AML who were between 17 and 60 years of age were randomly assigned to receive induction therapy with the standard dose of daunorubicin or twice the standard dose; the two groups also received a standard dose of cytarabine. Rates of complete remission and overall survival were best in the high-dose group, especially among patients with a favorable or an intermediate cytogenetic risk profile.
Comparative Efficacy of Inactivated and Live Attenuated Influenza Vaccines
Mercredi 23 Septembre 2009 - 08:56 - 5 mois, 3 semaines depuis   -  Santé  -  New England Journal of Medicin
Data are scarce regarding the comparative efficacies of the inactivated (intramuscular administration) and live attenuated (intranasal administration) seasonal influenza vaccines. During the 2007-2008 influenza season, 1952 healthy young adults were enrolled in a randomized, double-blind, placebo-controlled study of these two vaccines. The inactivated vaccine was found to have an absolute efficacy of 68%, whereas the live attenuated vaccine had an absolute efficacy of 36%.

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