Dernières entêtes d'Actus
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ORIGINAL ARTICLE: Duration of Androgen Suppression in the Treatment of Prostate Cancer
Mercredi 10 Juin 2009 - 08:55 - 3 semaines, 2 jours depuis - Santé - New England Journal of Medicin A current standard treatment for locally advanced prostate cancer is external-beam radiotherapy combined with 3 years of androgen suppression. Adverse events, such as myocardial infarction, are associated with long-term androgen suppression. This trial examined survival after treatment with long-term (3 years) or short-term (6 months) androgen suppression, plus external-beam radiotherapy, in men with locally advanced prostate cancer. Overall and prostate-cancer-specific survival in the group receiving short-term androgen suppression was inferior to that in the group receiving long-term suppression. |
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ORIGINAL ARTICLE: The Safety of Metoclopramide Use in the First Trimester of Pregnancy
Mercredi 10 Juin 2009 - 08:55 - 3 semaines, 2 jours depuis - Santé - New England Journal of Medicin This large cohort study showed no significant association between the use of metoclopramide in pregnancy and risks of adverse outcomes for the fetus, including risks of major congenital malformations. These findings provide reassurance regarding the safety of metoclopramide for the treatment of nausea and vomiting in pregnancy. |
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ORIGINAL ARTICLE: Zika Virus Outbreak on Yap Island, Federated States of Micronesia
Mercredi 10 Juin 2009 - 08:55 - 3 semaines, 2 jours depuis - Santé - New England Journal of Medicin Zika virus is a flavivirus known to cause human infection in Asia and Africa. This article describes an outbreak of Zika virus infection on Yap Island, Federated States of Micronesia, with predominant symptoms of rash, fever, arthralgia, and conjunctivitis. An estimated 73% of Yap residents 3 years of age or older became infected during the 4 months of the outbreak. |
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ORIGINAL ARTICLE: Primary Biliary Cirrhosis Associated with HLA, IL12A, and IL12RB2 Variants
Mercredi 10 Juin 2009 - 08:55 - 3 semaines, 2 jours depuis - Santé - New England Journal of Medicin A genomewide association analysis of patients with primary biliary cirrhosis suggests that variation in interleukin-12 signaling may confer a risk of disease. This study also firmly implicates variants at the HLA locus as a risk factor. |
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CLINICAL PRACTICE: Prenatal Screening for Aneuploidy
Mercredi 10 Juin 2009 - 08:55 - 3 semaines, 2 jours depuis - Santé - New England Journal of Medicin A 37-year-old woman, gravida 1, seeks prenatal care at 8 weeks' gestation. Her family history and medical history are unremarkable. What would you advise regarding her risk of fetal chromosomal abnormalities such as Down's syndrome and her options for prenatal screening and diagnosis? |
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IMAGES IN CLINICAL MEDICINE: Biliary Stones
Mercredi 10 Juin 2009 - 08:55 - 3 semaines, 2 jours depuis - Santé - New England Journal of Medicin A 63-year-old woman presented with a 2-day history of fever, abdominal pain, and vomiting. There was no history of previous episodes. Physical examination revealed fever and moderate abdominal tenderness in ... |
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IMAGES IN CLINICAL MEDICINE: Graves' Hyperthyroidism
Mercredi 10 Juin 2009 - 08:55 - 3 semaines, 2 jours depuis - Santé - New England Journal of Medicin A 42-year-old woman presented with palpitations, anxiety, tremor, and weight loss. She had received a diagnosis of Graves' disease 15 years previously but had discontinued therapy more than 5 years ... |
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CLINICAL PROBLEM-SOLVING: Kiss of Death
Mercredi 10 Juin 2009 - 08:55 - 3 semaines, 2 jours depuis - Santé - New England Journal of Medicin A 23-year-old South African man presented to an emergency department with a 2-day history of fever, mild dyspnea, headache, nausea, and myalgias. His symptoms had begun 5 days after he had traveled to Colorado to ski with friends. |
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EDITORIAL: Diabetes with Coronary Disease -- A Moving Target amid Evolving Therapies?
Mercredi 10 Juin 2009 - 08:55 - 3 semaines, 2 jours depuis - Santé - New England Journal of Medicin The prevalence of diabetes mellitus is rising at an alarming rate and is projected to more than double by 2030.1 The disease currently afflicts 171 million people worldwide, with 23.6 ... |
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EDITORIAL: Androgen Deprivation in Prostate Cancer -- Step by Step
Mercredi 10 Juin 2009 - 08:55 - 3 semaines, 2 jours depuis - Santé - New England Journal of Medicin Clinicians and researchers have debated the relative efficacy and timing of androgen deprivation since 1941, when Charles B. Huggins and Clarence V. Hodges reported that androgen deprivation reduced testosterone levels ... |
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-- Claude LÉVI-STRAUSS, Tristes tropiques, neuvième partie, XL
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