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ORIGINAL ARTICLE: Screening and Prostate-Cancer Mortality in a Randomized European Study
Mercredi 25 Mars 2009 - 06:56 - 11 mois, 3 semaines depuis   -  Santé  -  New England Journal of Medicin
In this trial, investigators tested the effect of prostate-specific-antigen testing on the death rate from prostate cancer in more than 162,000 men between the ages of 55 and 69 years in seven European countries. A significant reduction in prostate-cancer mortality was found after a median follow-up of 9 years. Overdiagnosis and overtreatment were important limitations of the screening program.
CLINICAL THERAPEUTICS: Pulmonary Rehabilitation for Management of Chronic Obstructive Pulmonary Disease
Mercredi 25 Mars 2009 - 06:56 - 11 mois, 3 semaines depuis   -  Santé  -  New England Journal of Medicin
A 61-year-old black woman with chronic obstructive pulmonary disease is referred for enrollment in a pulmonary rehabilitation program. Pulmonary rehabilitation includes high-intensity exercise to improve muscle function and reduce dynamic hyperinflation of the lungs, as well as education to promote collaborative self-management strategies. Patients with unstable angina or recent myocardial infarction may not be good candidates for pulmonary rehabilitation.
IMAGES IN CLINICAL MEDICINE: Penile Papules
Mercredi 25 Mars 2009 - 06:56 - 11 mois, 3 semaines depuis   -  Santé  -  New England Journal of Medicin
A 59-year-old man was referred to our hospital for the management of genital warts. Multiple, asymptomatic, smooth, round, skin-colored papules were observed at the corona of the glans penis. Physical ...
IMAGES IN CLINICAL MEDICINE: Mediastinal Extension of a Goiter
Mercredi 25 Mars 2009 - 06:56 - 11 mois, 3 semaines depuis   -  Santé  -  New England Journal of Medicin
A 67-year-old woman presented with a 6-month history of dyspnea and dysphagia. Physical examination revealed a small cervical goiter, but the lower poles of the thyroid were not palpable. The ...
CASE RECORDS OF THE MASSACHUSETTS GENERAL HOSPITAL: Case 10-2009 -- A 23-Year-Old Woman with an Abnormal Papanicolaou Smear
Mercredi 25 Mars 2009 - 06:56 - 11 mois, 3 semaines depuis   -  Santé  -  New England Journal of Medicin
A 23-year-old woman came to the adolescent and young adult medicine clinic at this hospital to establish care and to receive counseling regarding oral contraception, screening for sexually transmitted infections, and vaccination against human papillomavirus. Pathological examination of a Papanicolaou smear disclosed a high-grade squamous intraepithelial lesion. Additional diagnostic testing was performed, and management decisions were made.
EDITORIAL: Glucose Control in the ICU -- How Tight Is Too Tight?
Mercredi 25 Mars 2009 - 06:56 - 11 mois, 3 semaines depuis   -  Santé  -  New England Journal of Medicin
For the past decade, hospitals have focused on the inpatient management of hyperglycemia, particularly in the intensive care unit (ICU). Extensive observational data have shown a consistent, almost linear relationship ...
EDITORIAL: Prevention of Viral Sexually Transmitted Infections -- Foreskin at the Forefront
Mercredi 25 Mars 2009 - 06:56 - 11 mois, 3 semaines depuis   -  Santé  -  New England Journal of Medicin
Three landmark randomized, controlled trials conducted in South Africa, Uganda, and Kenya from 2005 through 2007 demonstrated that adult male circumcision reduced the acquisition of human immunodeficiency virus (HIV) by ...
EDITORIAL: Screening for Prostate Cancer -- The Controversy That Refuses to Die
Mercredi 25 Mars 2009 - 06:56 - 11 mois, 3 semaines depuis   -  Santé  -  New England Journal of Medicin
In the United States, most men over the age of 50 years have had a prostate-specific-antigen (PSA) test,1 despite the absence of evidence from large, randomized trials of a net ...
CLINICAL IMPLICATIONS OF BASIC RESEARCH: A Lesson in Tolerance -- Maternal Instruction to Fetal Cells
Mercredi 25 Mars 2009 - 06:56 - 11 mois, 3 semaines depuis   -  Santé  -  New England Journal of Medicin
Maternal microchimerism in fetal blood and tissue, which is probably a consequence of the induction of the regulatory T cells in fetal lymph nodes, has implications for immunosuppression and our understanding of autoimmunity.
CORRESPONDENCE: Azathioprine or Methotrexate Maintenance for ANCA-Associated Vasculitis
Mercredi 25 Mars 2009 - 06:56 - 11 mois, 3 semaines depuis   -  Santé  -  New England Journal of Medicin
To the Editor: In their prospective, open-label trial, Pagnoux et al. (Dec. 25 issue)1 compared azathioprine (at a dose of ...

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