ORIGINAL ARTICLE: Duration of Androgen Suppression in the Treatment of Prostate Cancer
Mercredi 10 Juin 2009 - 08:55 - 9 mois, 1 semaine depuis
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New England Journal of Medicin
A current standard treatment for locally advanced prostate cancer is external-beam radiotherapy combined with 3 years of androgen suppression. Adverse events, such as myocardial infarction, are associated with long-term androgen suppression. This trial examined survival after treatment with long-term (3 years) or short-term (6 months) androgen suppression, plus external-beam radiotherapy, in men with locally advanced prostate cancer. Overall and prostate-cancer-specific survival in the group receiving short-term androgen suppression was inferior to that in the group receiving long-term suppression.